Zhaoyang Li

 

Professor

Email:zyli@tju.edu.cn

Institute: Institute of Advanced Metal Materials

 

Education

·1996.09-2000.07 B.S. in Polymer Materials, School of Materials, Tianjin University

·2000.09-2003.03 M.S. in Materials Science, School of Materials, Tianjin University

·2003.09-2007.11 Ph.D. in Department of Orthopaedics, Faculty of Medicine, The University of Hong Kong

 

Work experience

·2007.11-2011.11 Postdoctoral Fellow, Department of Orthopaedics, Faculty of Medicine, The University of Hong Kong

·2009.11-2010.11 Postdoctoral Fellow, Department of Orthopedics, Johns Hopkins University School of Medicine

·2011.11- Associate Professor and Professor, School of Materials, Tianjin University

 

Research

·Research fields:

Research and Development of Bone Filling Materials, Surface Modification of Orthopedic Implants, Bone Biomechanics and Molecular Biology

·Courses taught:

Materials Surfaces and Interfaces, Introduction to Materials Engineering, Advanced Metal Functional Materials

 

Undertake projects

·Key Project of Tianjin Nature Fund: Research on Photothermal and Photodynamic Antimicrobial Coatings on Orthopedic Implant Surfaces, Project No.: 20JCZDJC00580, Year of Execution: 2020.04-2023.03; Chairperson.

·National Natural Science Foundation of China (NSFC) Facial Project: Interfacial bone metabolism study of microRNAs promoting osteointegration of titanium alloy implants, Project No. 51871163, Year of Execution: 2019.01-2022.12; Chairperson.

·National Natural Science Foundation of China (NSFC) upper-level project: the role and mechanism of organic strontium modification of decellularized bone matrix to promote bone regeneration, Project No. 31570970, Year of execution: 2016.01-2019.12; Chairperson.

·Tianjin Science and Technology Sea Project: Modification and Research and Development of Marine Bio-implant Materials, Project No.: KJXH2015-07, Execution Year: 2015.08-2017.07; Chairperson.

 

Iconic results

1. Mengjing Wang, Xiang Ge*, Zhenduo Cui, Shuilin Wu, Shengli Zhu, Yanqin Liang, Zhaoyang Li*, William Weijia Lu. Influences of strontium on the phase composition and lattice structure of biphasic calcium phosphate. Ceramics International. 2021, 47(11): 16248-16255.

 

2. Zhen Geng*, Luli Ji, Zhaoyang Li* Jing Wang*, Hongyan He, Zhenduo Cui, Xianjin Yang, Changsheng Liu. Nano-needle strontium-substituted apatite coating enhances osteoporotic osseointegration through promoting osteogenesis and inhibiting osteoclastogenesis. Bioactive Materials. 2021, 6(4):905-915.

 

3. Zhen Geng, Yuanman Yu, Zhaoyang Li*, Lili Ma, Shengli Zhu, Yanqin Liang, Zhenduo Cui*, Jing Wang*, Xianjin Yang, Changsheng Liu.miR-21 promotes osseointegration and mineralization through enhancing both osteogenic and osteoclastic expression. Materials Science and Engineering: C. 2020, 111:110785.

 

4. Xiaojun Sun, Zhaoyang Li*, Zhenduo Cui, Shuilin Wu, Shengli Zhu, Yanqin Liang, Xianjin Yang. Preparation and physicochemical properties of an injectable alginate-based hydrogel by the regulated release of divalent ions via the hydrolysis of d-glucono-δ-lactone. Journal of Biomaterials Applications. 2019, 34(7):891-901.

 

5. Wang Ying, Geng Zhen, Huang Yongcan, Jia Zhaojun, Cui Zhenduo*, Li Zhaoyang*, Wu Shuilin, Liang Yanqin, Zhu Shengli, Yang Xianjin. Unraveling the osteogenesis of magnesium by the activity of osteoblasts in vitro. Journal of Materials Chemistry B. 2018, 6(41):6615-6621.

 

·Invention patent authorization: 2016104127388, preparation method of sodium alginate coating with strontium chelated on titanium surface.

 

·Invention patent authorization: 2015105747985, an injectable antibacterial bone cement and preparation method and application.

 

·Invention patent authorization: 2014101551389, TC4 Preparation method of organic strontium coating on titanium alloy surface.

 

·Invention patent authorization: 2013105622919, a method for preparing graphene oxide layer on the surface of titanium by electrodeposition and its application.

 

·Industrialization achievements: In cooperation with enterprises, it has obtained 1 Class III medical device registration certificate (bone cement, National Machinery Approval 20193130757) and 1 Class II medical device registration certificate (medical image processing software, Guangdong Machinery Approval 20202212009).